June 21, 2024

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All You Need To Know About MGF Peptide and Its Uses

3 min read

MGF, also known as Mechano Growth Factor, is an amazing strength-boosting peptide that keeps the body energetic and active. This is a naturally occurring endogenous peptide that is of the IGF-1 class. As the human body grows and starts ageing, the strength of muscles in the body also starts declining. The reason behind it is that the growth hormone level decreases with increasing age, which directs its points to the less splicing of IGF-1 into MGF-1. MGF contains a total number of 49 base pairs at exon 5 and that is what differentiates it from IGF-1. MGF is also referred to as IGF-1Ec.

Ageing is not the only disorder that comes with an increasing age. Muscle dystrophy is also a disorder, which is also a reason why the reduction in MGF levels begins. MGF Peptide could prove to be very useful if someone wants to increase their muscle fitness and good health. There are very few or comparatively no side effects.  

How Is MGF Produced in the Body?

The very initial stage starts with the splicing of IGF-1, which results in the production of three different isoforms. The splicing of IGF-1 happens at the time of stress or resistance exercise. After this happens, the mature isoform is produced and that is what becomes the MGF. (The 49 added base pairs also have their role in the transformation process of IGF-1 to MGF).

Muscle Hypertrophy is then started by the functioning of MGF that further leads to the repair work of damaged muscles and strengthening of muscles etc. 

When was MGF discovered?

At the time of research studies of IGF-1, it was seen that the splicing process of IGF-1 and later on producing 3 Isoforms, resulted in the formation of MGF. The three isoforms were very similar to each of them and the only differentiation factor between them was the chain of amino acids attached to the COOH terminal. 

In the early 2000s, the fact of IGF-1 came to be known as it’s level was seen increasing significantly at the time of muscle injury. 

How Does MGF Work?

The working mechanism of MGF is quite simple to understand. It functions at the time of muscle stress, when the IGF-1 gene splices and produces MGF. 

After that, the main functioning of MGF starts in which MGF activates the muscle cells because of the attached chain of amino acids to its COOH terminal. 

What Are The Benefits of MGF?

MGF has many therapeutic benefits that are listed below –

  1. Faster wound healing
  2. It builds new muscles and strengthens them.
  3. It contains neuroprotective functions.
  4. Repairing tissues
  5. Bone injuries can be repaired.
  6. Lowers cell death.

What Are The Side Effects of MGF?

MGF has few side effects that occur in very few cases, which would be considered rare.

  1. Lowers blood sugar levels
  2. Low blood pressure
  3. Pain at the injected site
  4. Itchiness at the site.
  5. Vomiting
  6. Dizziness


Mechano Growth Factor is an isoform of IGF-1 and a very potent peptide. If you are also planning to buy MGF Peptide, then make sure you buy it from a trusted and safe place.